2 edition of effect of germ cell damage on animal reproduction found in the catalog.
effect of germ cell damage on animal reproduction
Animal Reproduction Symposium (4th 1959 University of Illinois)
in Champaign, Ill
Written in English
|Statement||sponsored by the College of Agriculture and the College of Veterinary Medicine.|
|Series||Journal of dairy science -- v. 43.|
|Contributions||University of Illinois (Urbana-Champaign campus). College of Agriculture., University of Illinois. College of Veterinary Medicine.|
|The Physical Object|
|Pagination||169 p. :|
|Number of Pages||169|
Animals specify primordial germ cells (PGCs) in two alternate modes: preformation and epigenesis. Epigenesis relies on signal transduction from the surrounding tissues to instruct a group of cells to acquire PGC identity. Preformation, thought to be the more derived PGC specification mode, is instead based on the maternal inheritance of germ cell-determining factors. Los Angeles, CA, USA – Scientists from the USC Stem Cell laboratories of Neil Segil and Justin Ichida are whispering the secrets of a simpler way to generate the sensory cells of the inner ear. Their approach uses direct reprogramming to produce sensory cells known as “hair cells,” due to their hair-like protrusions that sense sound waves.
This effect of testosterone suppression on the jsd mice has been shown to be due to increased testicular temperature in these animals while the effect on germ cell transplantation may be due to disruption of the blood-testis barrier allowing the stem cells to reach the Sertoli cell niche. The mechanism underlying the effect of androgen. Class 8 Reproduction in Human Beings Male Reproductive System: The male reproductive germ cell is called sperm. The formation of sperms takes place in the testes. The sperms are tiny bodies that consist of mainly genetic material and a long tail that helps them to move towards the female germ-cell.
Study question: Does the Irinotecan metabolite 7-ethylhydroxycamptothecan (SN38) damage the gonads of male and female prepubertal mice? Summary answer: The Irinotecan metabolite SN38 reduces germ cell numbers within the seminiferous tubules of mouse testes at concentrations that are relevant to cancer patients, while in contrast it has little if any effect on the female germ cell population. Explore the latest full-text research PDFs, articles, conference papers, preprints and more on INVERTEBRATE REPRODUCTION. Find methods information, sources, references or conduct a .
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The effect of germ cell damage on animal reproduction. Fourth Symposium, June, University of Illinois, Urbana.
Author(s): UNITED STATES]: BIENNIAL SYMPOSIUM ON ANIMAL REPRODUCTION. Evaluation of Germ Cell–Specific Proteins in IF Following Toxicant Treatment.
The germ cell–specific proteins, VASA and FABP9, were selected for investigation as potential biomarker candidate proteins. VASA and FABP9 were measured in IF samples from animals treated with the toxicants, using Western by: Sertoli cells (SC s) play a central role in the development of germ cells within functional testes and exhibit varying morphology during present study investigated the seasonal morphological changes in SC s in the reproductive cycle of Pelodiscus sinensis by light microscopy, transmission electron microscopy (TEM), and by: 8.
In another study, the effect of cobalt–chromium nanoparticles on human trophoblast choriocarcinoma cell lines and a layer of BeWo b30 cells was examined, and DNA damage in the fibroblasts was noted despite indirect exposure (Bhabra et al.
In summary, the listed findings highlight how various developing organisms react to by: In the second, transplanted germ cells were present in the seminiferous epithelium 4 weeks after the transfer. These cells were morphologically identified as B-spermatogonia and located at the base of the seminiferous epithelium.
In summary, this paper describes a promising approach for germ cell infusion into large by: The present study outlines a preclinical approach using a non-human primate to study the feasibility, side effects and efficiency of restoration of autologous germ cell transplantation after X-ray-induced germ cell loss mimicking the testicular damage.
Sperm is the male reproductive cell, or gamete, in anisogamous forms of sexual reproduction (forms in which there is a larger, "female" reproductive cell and a smaller, "male" one). Animals produce motile sperm with a tail known as a flagellum, which are known as spermatozoa, while some red algae and fungi produce non-motile sperm cells, known as spermatia.
In genetics, a mutagen is a physical or chemical agent that changes the genetic material, usually DNA, of an organism and thus increases the frequency of mutations above the natural background level.
As many mutations can cause cancer, mutagens are therefore also likely to be carcinogens, although not always necessarily mutagens have characteristic mutational signatures with some.
A significant increase of germ cell death in the meiotic zone of the gonad was observed in worms exposed to endosulfan at concentrations of1, and 10 µM for 12 h, respectively.
The germ cell corpses in worms exposed to 10 µM endosulfan was. In animals, where DNA damage can be experimentally induced in the paternal germ line, strong associations have been shown between damage to the paternal genome and embryo development including effects on the new born and subsequent generations [6,7].
These experiments are not feasible in humans, but provide clear warnings of the impact that. Because of envenomation, DNA damage may be detected in circulating erythrocytes, and nuclear blood cells, as well as in testicular cells.
Such damage in spermatogenic cell lineages can lead to reproduction disorders, especially when spermatogonia are affected, because such cells represent the genetic and cellular reservoir of sperm cells in.
Introduction. The effects of radiation on the reproductive system in humans have been extensively explored through events in which a large number of the population were exposed (Harley,Harley, ).Many of these studies are now well known, such as the case of radium dial painters, survivors of the atomic bomb, workers and residents around Chernobyl and uranium miners exposed.
Since the male germ cell is very compact and rigid in nature, DNA damage due to EMF is significant. However, a short-term effect of RF exposure is not strong and effective enough to cause any genomic level of changes because this damage may be the result of cumulative effects.
Objective: To study the reproductive damage of sperm and testicular germ cell induced with adriamycin in male mice.
Methods: 60 male mice were randomly divided into three groups equally. Adriamycin 3 -1 was injected to A group, Adriamycin 5 -1 was injected to B group, and physiological saline was injected to C group (control group) for 5 days. DNA damage can also be repaired by other mechanisms not discussed here such as direct reversal, mismatch repair (MMR), homologous recombination (HR) and non-homologous end joining (NHEJ) (recently reviewed in germ cells by Baarends et al., ).
DNA excision repair in germ cells. There is limited information on repair functions in male germ cells. These findings indicate a highly protective effect of the antagonist with a significant protective ratio of for the 50 mg/kg Cy dose, and a lower but still significant protective ratio of for the 75 mg/kg Cy dose.
As expected, the addition of cetrorelix to untreated control animals did not have any effect. It takes much longer for the biological effects to become apparent. If the damage is sufficient to kill the cell, the effect may become noticeable in hours or days.
Cell "death" can be of two types. First, the cell may no longer perform its function due to internal ionization; this requires a dose to the cell of about gray (10, rad). Techniques to alter a gene sequence that result in an inactivated gene, or one in which the expression can be inactivated at a chosen time during | Explore the latest full-text research PDFs.
Explore the latest full-text research PDFs, articles, conference papers, preprints and more on CELL SURFACE MARKERS.
Find methods information, sources, references or conduct a. An oocyte (UK: / ˈ oʊ ə s aɪ t /, US: / ˈ oʊ oʊ-/), oöcyte, ovocyte, or rarely ocyte , is a female gametocyte or germ cell involved in other words, it is an immature ovum, or egg oocyte is produced in the ovary during female female germ cells produce a primordial germ cell (PGC), which then undergoes mitosis, forming oogonia.
Abstract. The influence of exogenous glucocorticoid, dexamethasone (Dex), on testicular germ cell apoptosis was investigated in rats. The percentages of apoptotic tubules and apoptotic germ cells in the Dex-treated group of rats were about seven-fold and fold higher respectively than in either the control group, or in rats treated with glucocorticoid receptor agonist (GR-A), or in rats.Coogan T, Rosenblum I and Barsotti D () Bleomycin-induced DNA-strand damage in isolated male germ cells, Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, /(86),(), Online publication date: 1-SepThe protective effect of AS against the adverse effect of Cy on the number of impregnated animals and on the litter size could be attributed to the protection against the significant increase in sperm chromatin damage, which has been shown to reduce fertilization rates and cause post-implantation embryo loss in animals (Codrington et al.